Serrapeptase is a powerful enzyme known for its anti-inflammatory effects. It can help reduce swelling, improve joint mobility, and support overall health.

However, some people claim to have experienced digestive issues from taking Serrapeptase, such as bloating and stomach pain.

In this blog post, we will discuss how to safely take Serrapeptase so that you can reap the benefits of this enzyme without any digestive discomfort.


What Is Serrapeptase?

Serrapeptase is an enzyme that occurs naturally in silkworms but is now manufactured on a plant base, so is considered to be vegan-friendly. It has been studied extensively over the past few decades and has been found to have several beneficial properties.

Its most notable benefits are its anti-inflammatory effects, which can help to dissolve inflammation and dead scar tissue safely and effectively in the body, providing natural relief for various health conditions. Supporting the body’s ability to break down scar tissue can also promote healthy circulation and lymphatic drainage.


How To Take Serrapeptase Safely

While Serrapeptase is generally safe for most people when taken as directed, a few people may experience digestive issues such as bloating or stomach pain.

To prevent these issues, there are a few steps you can take to ensure the safe use of this enzyme:


1. Start with a low dose

Begin with one capsule per day and slowly increase your dosage until you reach your desired results. Starting with a low dose will help minimise any digestive discomfort you may experience while allowing your body to get used to the supplement before increasing the dosage.


2. Take on an empty stomach

Taking Serrapeptase on an empty stomach is recommended as the enzyme can work more effectively. By doing this, the Serrapeptase enzyme works on the body’s system rather than the digestive process. This can help to support the body’s healing process.


3. Address the underlying digestive health imbalances

If you take Serrapeptase and continue to experience nausea or sickness, assessing your gut microbiome is essential. An underlying digestive health problem may be causing these unwanted issues.

Addressing these underlying digestive factors first can create a balance in gut health. If you have poor gut health, or underlying digestive issues, this is possibly due to digestive imbalances or toxicity that have not been addressed.


4. Consider Probiotics

You can address underlying digestive factors by taking probiotics, which can replenish your gut bacteria. As a result, this creates a balance in gut health.

Taking probiotics for a few months can restore the gut bacteria balance. [1] Once you are satisfied that your gut flora is replenished, you can take the Serrapeptase and see how your body responds.


5. Try Sodium Butyrate

As a postbiotic, Sodium Butyrate is recommended to support the gut bacteria and aid the healing of the gut lining. Postbiotics can deliver compounds to the gut and often with immediate effect. One 2020 review on postbiotics found that they can help reduce and shorten diarrhoea symptoms. [2]

Other studies have also demonstrated how taking postbiotics may help to lower the risk of respiratory infections, improving their ability to produce antibodies that help defend the body against harmful bacteria and toxins. [3]

Sodium Butyrate is beneficial for conditions such as Irritable Bowel Syndrome (IBS), diverticulitis and Crohn’s disease.



Taking supplements like Serrapeptase can be beneficial for numerous reasons. If you’re struggling with some unpleasant issues, then there are ways to resolve this naturally, so you can receive the benefits of Serrapeptase.

By following these tips—starting slow, taking the Serrapeptase enzyme on an empty stomach, and addressing the underlying digestive health imbalances such as by taking probiotics or postbiotics to support gut health—you can reap all of the benefits of this powerful enzyme without worrying about any nasty issues.

With some planning, you can easily enjoy the Serrapeptase supplement’s wonderful benefits!







Recommended Examples


Prescript-Biotics™ – Our double award-winning probiotic supplement contains custom-cultured microflora to rebalance good gut flora. PrescriptBiotics contains SBO Probiotics Consortia™ that are missing from the modern diet. It may support the digestive process, immunity and overall good health. Suitable for vegetarians and vegans. 90 capsules. Available from Good Health Naturally.

Sodium Butyrate

Sodium Butyrate – A short-chain fatty acid, it’s one of the three most common SCFA’s in your gut, and the building blocks our cells need to function. It supports digestive health and provides immune health benefits. Suitable for vegetarians and vegans. 60 vegetable capsules. Available from Good Health Naturally.