Scientific Studies That Provide Proof

  • Konig, W.: Enzyme therapy in the treatment of viral diseases and carcinoma. 38, 1989, 455-459.
  • Kakinumu, A. et al. Regression of fibrinolysis in scalded rats by administration of serrapeptase. Pharmacol. 31:2861-2866, 1982.
  • Mazzone A, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
  • Serrapeptase and Nattokinase intervention for relieving Alzheimer’s disease pathophysiology in rat model. Hum ExpToxicol. 2013 Jul;32(7):721-35. doi: 10.1177/0960327112467040.
  • Kee WH. Tan SL, Lee V. Salmon YM. The treatment of breast engorgement with Serrapeptase: a randomised double blind controlled trial. Singapore MedJ. 1989:30(1): 48-54.
  • A preliminary trial of serratiopeptidase in patients with carpal tunnel syndrome. J Assoc Physicians India. 1999 Dec;47(12):1170-2.
  • T. and Mitsui, S. Effects of Serrapeptase in dissolution of sputum, especially in patients with bronchial asthma. Jap.Clin. Exp. Med. 49:222-228, 1972.
  • Kase, Y. et al. A new method for evaluating mucolytic expectorant activity and its application. II. Application to two proteolytic enzymes, Serrapeptase and seaprose. Arzneimittelforschung 32:374-378,1982
  • A technique for quantitative cytology of nasal secretions. Eur Arch Otorhinolaryngol. 1991;248(7):406-8.
  • Y. et al. Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus. Am. Rev. Respit. Dis. 141:79-83.1990.
  • Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars. Int J Oral Maxillofac Surg. 2008 Mar;37(3):264-8. doi: 10.1016/j.ijom.2007.11.011. Epub 2008 Feb 12.
  • Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars. Int J Oral Maxillofac Surg. 2008 Mar;37(3):264-8. doi: 10.1016/j.ijom.2007.11.011. Epub 2008 Feb 12.
  • Development of serratiopeptidase (and others) based alginate microspheres for wound healing. Artif Cells Blood SubstitImmobilBiotechnol. 2011 Feb;39(1):44-50. doi: 10.3109/10731199.2010.494580. Epub 2010 Jun 17.