Serrapeptase Articles


The serrapeptase enzyme has been successfully used in European and Asian pharmacology for over three decades. The reason for its use in these parts of the world is that it has proven successful in the treatment of a wide range of medical conditions and its use as an analgesic has been praised, because it has no side effects such as aspirin, ibuprofen, or opiates.

The serrapeptase enzyme is a naturally occurring enzyme, which is part of the silkworm’s body chemistry. The silkworm uses this enzyme to dissolve its protective cocoon, so that it can emerge as an adult moth. The same qualities which make this an effective digestive enzyme, make it equally effective in dissolving problematic tissue in the human body. Histological studies have evidence, which illustrates how it can dissolve cysts, scar tissue, mucous membrane, necrotic tissue, embolisms, and arterial plaque.

This enzyme is beneficial in treating repertory infections, which produce excessive mucous and pus. The mucous membrane can become so dense, along with excessive leukocytes production that the patient’s lung capacity is dangerously diminished. This enzyme helps to metabolize the mucous and leukocytes, allowing the patient to successfully expectorate them from their body. This increases the body’s ability to take in oxygen, which in turn promotes healing of the infected lung tissue.

This enzyme works as an analgesic, because it blocks the pain receptors in the damaged tissue. Scientific studies have found there are no detrimental side effects to its use in palliative care. Patients can safely use this enzyme regimen without concern of any damaging effects to their liver, heart, or intestinal track. The use of this advantageous enzyme is gaining approval in Western pharmacology and medical practices. More scientific research needs to be completed before it receives full recognition for its use in palliative care and creating healthy tissue. The studies have all been extremely positive and this enzyme’s use in Western medicine is not far off.



Modern Applications of Proteolytic Enzymes

The development of proteolytic enzyme therapy can be attributed to Max Wolf, a scientist who authored a book on the science of endocrinology. While this might be a very popular branch of science, it was not developed as it is today. Max Wold with his colleague, Benitez, carried out research studies on the subject between the 1930s and 1970s. Their research dealt with various combinations of different enzymes but did not have strict controls that are used in modern research studies. The two scientists were able to observe the effects of enzyme therapy on lymph edema, viral infections and vascular diseases. They also noted that enzyme therapy was instrumental in the healing of injuries and inflammations. Their observations made them conclude that a deficiency in proteolytic enzymes contributed to premature aging.

These enzymes are also known to help with urinary tract infections. Clinical investigations in Europe have revealed that when the enzyme is used in conjunction with ampicillin, trimethoprim and tetracyclines or any other antibiotic drug, a higher concentration of the antibiotic drugs went to the infected area. This means that the person that has the infection can be cured more rapidly.

One example of this enzyme is serrapeptase. Scientists have found that this enzyme is superior to other proteolytic enzymes because of its unique anti-inflammatory effect. This enzyme is completely bound to macroglobulin biological fluids such as alpha 2.

Proteolytic enzymes can also be used to treat serious illnesses like Rheumatoid arthritis (RA). Normally, D-penicillamine, steroidal and non-steroidal anti-inflammatory medications and methotrexate are used to treat RA. These drugs are potentially dangerous and they only offer short-term relief. They can be fatal if not used according to doctor’s advice.

According to research studies carried out over the years, proteolytic enzymes can be used to manage symptoms of rheumatoid arthritis better than most conventional drugs. The best thing about this enzyme therapy is that it does not have side effects.



The right serrapeptase dosage depends on several factors. It can be prescribed for conditions such as Type 2 diabetes and certain cardiovascular problems. Most physicians recommend between one and three tablets to be taken on an empty stomach. The amount of medicine in capsule form is calculated in iu measurements. A standard prescription of 90 capsules has roughly 80,000 iu per capsule. They can also contain trace amounts of various minerals that do not interfere with the main ingredient’s chemical action.

Some people are given a serrapeptase dosage for blockages in their arteries. Some doctors will write an initial prescription for 40,000 IUs per capsule, which is also sometimes called a “blockbuster” dosage. Patients with more serious arterial blockages may also be given a secondary medication for quicker symptom relief. Both of these medications may be adjusted according to different health conditions. Common secondary medications include Curcumin X-4000 or OxySorb. Patients under a doctor’s care for artery blockages are also advised to follow a healthy diet along with treatment. Some may be advised to make significant dietary changes in order to keep arterial blockages from building up and worsening.

Serrapeptase does not have a current upper limit for standard dosages. Many physicians report that extra dosages are helpful in most cases. They usually tell their patients to take the medication at least 30 minutes prior to eating in order to avoid any possible interference or unpleasant side effects. They also emphasize the importance of exercise and diet while taking this medicine.

Some people report that they see little improvement in their conditions during the first few weeks of treatment. A recommended reduced dosage is about three capsules per day for three or four months unless otherwise advised. Many people on this course of treatment also keep records of any noticeable changes in their condition, whether positive or negative.

A serrapeptase dosage is sometimes prescribed for reducing the appearance of scars on the skin, whether from surgical procedures or from injuries. Doctors often report that different patients respond to this treatment after a few months of consistent dosage. Skipping dosages can lead to fewer positive results in many cases. Improvement can also depend on skin elasticity and on any other health conditions that may interfere with the serrapeptase in some cases.



The proteolytic enzyme, serrapeptase, is taken to ease inflammation. This particular protease is used as it effectively dissolves dead and swollen tissue.

I first published information to the internet in 2000, after a San Diego pioneer first educated me on its properties. I researched 23 studies on this compound, and started to prescribe it to clients who were exhibiting comparable symptoms. Dosages were in the order of 10,000IU for patients who were taking part in the early studies, but varying mega dosages were administered to other clients. Intake was progressively increased, and I soon found out that the studies were correct, as it was working as well as what was indicated, with superior results at higher doses. I am now 67 and have been taking as much as 240,000IU for the last 13 years on a daily basis. I am convinced that my excellent health is partly as a result of using this product.

Doctors and other individuals have released information to the internet community based on my findings. A concern is that these reports express opinions about serrapeptase side effects, but are not based on any real life experiences. With hundreds of thousands of clients that I have helped giving me feedback, as well as my own experiences with the product, my opinions are solely based on the feedback from these clients. There were two claims by a couple of doctors in Japan that serrapeptase had caused a lung infection. This has not been duplicated from hundreds of thousands of users in the past twenty years and all I can surmise is that they were mistaken. It is not the first time in my experience that doctors were mistaken.

Serrapeptase seems to be safe to use for adults and children when consumed orally. Taking it several times a week, and then stopping will allow an individual to accurately assess its effects or effectiveness. 99.9% of my clients, as well as my children and other family members, have all reported no side effects. Long term effects have not had any formal documentation.

Warning: If you are in search of information about serrapeptase then ensure that the health care professional is well educated in the field of enzymes and how they play an important part in overall health.

Quite a few of my clients, as well as my daughters, were taking serrapeptase during their pregnancies, as well as during breastfeeding. Serrapeptase has been highly effective in women who have endured scar tissue inside their fallopian tubes. They were all able to have healthy pregnancies and babies, while taking serrapeptase with other supplements and using a carb-free diet.

Excessive bleeding: There are warnings that point out that serrapeptase can stop blood from clotting and exacerbate bleeding problems. The majority of these warnings are stated by people who are not aware of how this substance produces its results. My findings indicate that it does not cause unusual bleeding and the only cases reported were those who already had problems, e.g. with nose bleeds.

Usage during surgery: My personal recommendation is to stop the intake at least 24 hours before a surgery and continue when 24 to 48 hours have passed. This can help clear up any scar tissue, and stop lesions and adhesions from occurring.

Digestive system: Taking any proteases with a poor digestive system may cause discomfort or pain in certain individuals. Ingesting with a half teaspoon of bicarbonate in your 500ml glass of water may help to alleviate this. If you do experience continued pain from digestive problems then email me personally, and I will send you a plan for your digestive recovery before you continue with the use of serrapeptase.

Interactions with other drugs: Serrapeptase is safe to use with all drugs as well as warfarin, statins and aspirin.



Serratiopeptidase is an enzyme that originates in the intestine of the silkworm at the time that the silkworm becomes a moth. It is derived from Serratia E15, a non pathogenic bacterium. Anyone suffering from bronchitis or post traumatic swelling, fibrocystic breast disease can benefit from the enzyme’s anti-inflammatory qualities.

The following substances are able to be absorbed by the enzyme:

  • Dead tissue
  • Blood clots
  • Cysts
  • Arterial plaques
  • Scar tissue
  • Respiratory venues that have mucus build-up

Neutrophils, which are commonly used to fight infection, are the most common of the white blood cells in the body, and serratiopeptidase is so effective in reducing mucus in respiratory pathways because it is able to reduce the number of neutrophils. The elasticity of the mucus or phlegm is improved because there are fewer white blood cells, meaning that those with a chronic airway disease can get rid of any infection.

Serratiopeptidase also has the added benefits of being able to reduce pain, minimize heart problems and reduce the chance of liver and kidney problems, especially with those who overuse ibuprofen, aspirin and other anti-inflammatory drugs. It is able to block pain so effectively because molecules that cause the pain are blocked from tissue that has been irritated.

The enzyme is still being slowly introduced to both Canada and the US, although it has been used in Asia and Europe for more than 30 years. The results of initial research are encouraging and the enzyme has attracted the interest of several supplement manufacturers.



I informed you some years ago that Serrapeptase is apparently active in the cleaning of coronary arteries from occluding layers. The results are so spectacular that even Tom Valentine reported on this progress in the US (DC) press after speaking to several parties here.

Serrapeptase is an enzyme produced by serratia bacteria living on silkworms. With this enzyme the worms melt a hole out of the cocoon. Unlike other enzymes in the field of biology, Serrapeptase dissolves ‘dead’ tissue, leaving the living tissue unharmed. This is interesting as fibrinoid layers in the arteries could be chemically compared to silk.

A special problem in today’s civilized society is occluding processes in the carotid arteries of the neck. Very often we see patients where surgeons were reluctant to operate or to apply drill or laser technology to such occluded carotids. The reason for this is the potential risk that off-coming debris will be pushed into the smaller cerebral vessels.

We have, therefore started to apply Serrapeptase in cases of severe narrowings of the carotid arteries. Mostly in patients showing severe symptoms due to the narrowing, including amaurosis fugax (intermittent blindness). The therapeutic results are excellent, certainly lifesaving. It is, however, mandatory that the therapy be conducted for a very long time. The first reliable results can be expected after 6-8 months. Even after month 18, after the onset of the therapy, the patients are improving.

I have also found Serrapeptase to be an extraordinary substance for safely removing fibrous blockages from coronary arteries, particularly the carotid arteries found in the neck, which supply blood to the brain. Serrapeptase is a natural enzyme produced by serratia bacteria living in silkworms. Once the silkworm has completed its transformation into a moth, it uses this substance to “melt” a hole in its cocoon, so that it can escape.

The astonishing fact is that, unlike other biological enzymes, Serrapeptase affects only non-living tissue, like the silk cocoon. This is the reason the butterfly is not harmed. For our health purposes, Serrapeptase dissolves only dead tissues such as the old fibrous layers that clog the lining of our arteries and dangerously restrict the flow of blood and oxygen to the brain. Because of this, Serrapeptase is extremely useful in keeping arterial deposits from building up again after angioplasty (a balloon technique used to clear an artery blockage) or coronary bypass surgery has been performed.

Very often, surgeons are reluctant or unable to open partially closed carotid arteries using laser surgery. They fear that resulting debris could be pushed into smaller connecting arteries and result in a stroke and possibly death. In cases of severe arterial narrowing, I have used Serrapeptase with excellent, even life-saving results. Many of my patients have shown significant improved blood flow through their previously constricted arteries, as confirmed by ultrasound examination. Unfortunately, orthodox cardiologists do not employ this important method in their practices.

Dr H. A. Nieper

Head, Dept of Medicine

Paracelcus Klink am Silbersee Oertzeweg 24

38051 Langenhagen, Germany

Article by: Dr. H A Nieper


Article by: Jenny Pulling

‘Ripples on water, the myriad shapes of leaves and plants: because of my poor eyesight I never expected to see these beauties. They were limited to my imagination based on friends’ descriptions. Now everything has changed, I am seeing the world with fresh eyes.’ This poetic description of Mike Tawse’s regained sight marks the latest chapter in his Serrapeptase Adventure.

The inspiring story of one man’s victory over his life-threatening health condition even persuaded Robert Redfern to rename his book ‘The Miracle Enzyme is Serrapeptase’. Says Robert: ‘I was finally convinced to change the name of the book and to create an accompanying web site when the story of Mike Tawse first surfaced.’

It begins in December 2005, The scene: a ground floor flat near Manchester University, The 36 year old sits in his wheelchair – as he has for the previous ten years – and wonders if he will have (or wants) another year of life. Born with cerebral palsy he is now hardly able to speak, the fluid from his lungs nearly choking him, his heart and lungs failing. His concerned friends are so anxious they have discussed what arrangements he wants for his funeral.

The turning point came on January 3, 2006 when Mike was persuaded to start taking 2 SerraEnzyme tablets twice a day. A friend had heard how an enzyme called Serrapeptase was achieving a reputation for its power as an anti-inflammatory, pain reliever and for clearing away inflamed tissue in the body. What followed is an incredible journey, spanning two years, that has taken Mike from a purgatory of illness to the joy of health.

He started a blog, ( which became an ongoing message of inspiration. As he says: ‘The reason for putting my story out there was not so much for myself but worth it if just one person read it and was persuaded to try this route.’

Results came thick and fast. 24 Feb 2006 Mike wrote: ‘For the last seven days, my lung function has been great. It has been no lower than 500 litres per minute, and usually around 530 litres. It seems to me that it may well be settling. My heart rate remains normal, and even the condition of my skin seems improved. I have now completely stopped all my prescription medication and continue to feel stronger, eating and sleeping better.’

May 25, 2006. This is a celebratory blog as Mike describes his ‘first twenty steps’. ‘For several weeks, I have been experimenting with standing, with crutches, but not had the confidence to walk. After recovering from a stomach bug, I got back on my feet thinking I would stand for a few minutes, and that would be that. After about five minutes, my phone rang. Without conscious thought, I found I had taken the 20 steps to answer it. It was yet another sign I was regaining control over my condition instead of it having control over me.’

Life, which had seemed to be diminishing, now opened up. Mike was invited onto the Power Hour, an American talk show hosted by Joyce Riley. She had previously interviewed Robert Redfern about help for cerebral palsy. He described Mike’s experience.

Says Mike: ‘Joyce has a strong spiritual faith. One of the questions she asked me was, ‘Do you believe in miracles?’ I replied, ‘If I didn’t in the past I do now.’

Five months later, he wrote: ‘After careful, detailed checks of my heart function, blood pressure and lung function, all confirmed as normal, it has been agreed that I am very unlikely to need prescribed medication ever again.’

As Mike points out, there is a lot of confusion surrounding cerebral palsy. There are people who believe it is an illness that can be cured, whereas it is a condition that, as he has proved, can be ameliorated. However, the dramatic improvement in his eyesight and visual perception remains a mystery factor. This second year of Mike’s Serrapeptase Adventure has undoubtedly been dominated by this event. He feels it is the most exciting and unexpected of all.

‘It is obvious to me that the problems with my heart, lung function and digestive system were most likely caused or exacerbated by the medication I was given to manage the symptoms. Serrapeptase gave me a way of managing my condition without them and the chance to recover from their effects.

My development of depth perception is very different. The reason why I have never experienced it before is a direct result of the underlying brain damage. To the best of my knowledge, it is not possible to recover a skill never previously available. The dramatic improvement in my vision remains the mystery factor.

Robert Redfern described Serrapeptase as ‘the miracle enzyme’; it is a description I believe is well deserved.’

Mike Tawse: Serrapeptase Gave Me Back My Life… The progress continues today, in 2009. Please visit my website, to read the full story.